Soft tissue lesions in the pediatric population can vary widely in appearance and presentation. The most common benign tumor of infancy is a hemangioma which falls under the category of vascular anomalies. These, and other vascular skin lesions are discussed in greater detail here. Other common lesions include cysts, in particular dermoid cysts, which are discussed here. Lesions may be also be pigmented, and may fall under the category of nevi.
Another category of common pediatric skin lesions are pilomatricomas. These are benign (non-cancerous) structures comprised of hair follicle matrix cells. These have also previously been called “calcifying epithelioma of Malherbe”. They are slow-growing hard subcutaneous masses with a blue hue or ulcerative appearance. They can be found anywhere on the body, but most commonly the scalp, cheek, neck, the preauricular area, and the periorbital area. These lesions usually exist as solitary nodules, however, they may also be associated with Turner’s syndrome, Gardner’s syndrome, and myotonic dystrophy. These are treated by surgical excision.